BGC > Buscar Producto > Ots514 hydrochloride | 2319647-76-0

Description:
The hydrochloride of OTS514. OTS514 is a potent TOPK (T-LAK cell-originated protein kinase) inhibitor (IC50 = 2.6 nM), with an inhibitory effect on small cell lung cancer (SCLC). It acts through suppressing growth of SCLC cell lines and inducing their apoptotic cell death.

• Molecular Weight:400.92
• Purity:99.42 %

Molecular Formula:
C21H20N2O2S.HCl
Canonical SMILES:
CC1=CC(=C(C2=C1NC(=O)C3=C2C=CS3)C4=CC=C(C=C4)C(C)CN)O.Cl
InChI:
1S/C21H20N2O2S.ClH/c1-11-9-16(24)17(14-5-3-13(4-6-14)12(2)10-22)18-15-7-8-26-20(15)21(25)23-19(11)18;/h3-9,12,24H,10,22H2,1-2H3,(H,23,25);1H/t12-;/m0./s1
InChIKey:
CQPRMBOOBXSZSP-YDALLXLXSA-N
Solubility:
DMSO Solubility: 80 mg/mL (199.54 mM)
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
OTS 514 hydrochloride; OTS-514 hydrochloride; OTS514 HCl